Predictive factors associated with long-term survival in patients with...
AbstractBackgroundNeuroendocrine tumors of the pancreas are rare tumors. We identified predictive factors that are associated with long-term survival (≥5 years).MethodsFifty patients with a diagnosis...
View ArticleShould Adjuvant Therapy Remain the Standard of Care for Patients With...
AbstractAdenocarcinoma of the pancreas continues to be a formidable disease. In the United States, patients who have had resected disease are generally offered adjuvant chemoradiation. The current...
View ArticleCarcinoid Tumors
AbstractCarcinoid tumors are neoplasms derived from neuroendocrine cells and are widely distributed throughout the body in almost any organ. The traditional classification of carcinoid tumors includes...
View ArticleAdrenal Lesions
AbstractThe adrenal glands are complex and consist of the outer cortex and inner medulla. The cortex produces steroid hormones such as cortisol, aldosterone, and testosterone, while the medulla...
View ArticlePancreatic Neuroendocrine Tumors (PNETs)
AbstractPancreatic neuroendocrine tumors (PNETs) are tumors that arise from hormone-secreting cells of the islets of Langerhans; however, not all tumors will be associated with a clinical syndrome of...
View ArticleHereditary Colorectal Cancer and Polyposis Syndromes
AbstractColorectal cancer (CRC) is the second leading cause of death in the United States, with approximately 10–30 % of patients having a positive family history. Lynch syndrome is the most common...
View ArticleEsophageal Cancer
AbstractEsophageal cancer is a multifaceted disease that demands a multidisciplinary approach. Given its origin in the cervical neck and termination in the abdomen at the gastroesophageal junction,...
View ArticleSquamous Cell Carcinoma of the Anal Canal
AbstractAnal cancer is infrequent but the incidence is rising. Better understanding of the pathogenesis, natural course, and the results of clinical trials have resulted in improvement in management of...
View ArticleColon Cancer
AbstractColon cancer is a common disease that affects a significant number of people, both in the United States and worldwide. Surgery is the primary treatment for patients with resectable colon...
View ArticleMultiple Endocrine Neoplasia (MEN) Syndromes
AbstractThere are several hereditary syndromes associated with endocrine or neuroendocrine dysfunction. Examples such as von Hippel-Lindau syndrome and its association with pancreatic neuroendocrine...
View ArticleSmall Bowel Cancer
AbstractSmall bowel cancers comprise a rare group of neoplasms that account for 1–5 % of all gastrointestinal cancers. These cancers include adenocarcinoma, carcinoid, lymphoma, gastrointestinal...
View ArticleBRCA1 and BRCA2 in Breast Cancer and Ovarian Cancer
AbstractMutations of the BRCA1 and BRCA2 genes are known to confer an increased risk of breast cancer and ovarian cancer. These gene mutations are inherited in an autosomal dominant fashion and are...
View ArticleCholangiocarcinoma
AbstractCholangiocarcinoma (CCA) is an uncommon but lethal cancer arising from the bile duct epithelium. The clinical presentation depends on the site of origin and stage of the malignancy. The...
View ArticleLocally Advanced Breast Cancer (LABC)
AbstractLocally advanced breast (LABC) consists of inflammatory breast cancer (IBC) and non-IBC locally advanced breast cancer (non-IBC LABC).Although the diagnostic work-ups and management are...
View ArticleSoft Tissue Sarcoma
AbstractSoft tissue sarcomas are rare tumors derived from mesenchymal cells. The histologic diversity of sarcomas is vast, and new discoveries in molecular alterations are enhancing our understanding...
View ArticleGastric Cancer
AbstractGastric cancer remains a global health problem. Delayed diagnosis compounded by nutritional decline associated both with the disease and the treatment often complicates its management. While...
View ArticleRectal Cancer
AbstractSimilar to other solid malignancies, patients with rectal adenocarcinoma require a multidisciplinary approach to optimize their outcomes. The management of high-risk resectable rectal cancer...
View ArticleEarly Breast Cancers
AbstractThe management of patients with early breast cancer (EBC) has dramatically evolved over the past decades. The rapid pace of progress and the frequent shift in treatment paradigms have...
View ArticleMelanoma
AbstractMelanoma is a significant oncologic problem, affecting 2 % of people in the United States in their lifetime, many of whom are young. Risk factors for melanoma are multifactorial, including sun...
View ArticlePancreatic Adenocarcinoma
AbstractPancreatic ductal adenocarcinoma is the most common and most aggressive form of pancreatic cancer. A solid exocrine tumor arising from the pancreatic ducts, it comprises approximately 90 % of...
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